Sample questions / Nervous System
Organ systemWork through nervous system vignettes that mix physiology, pathology and pharmacology, the way the exam does. Every explanation covers all five options.
A 52-year-old woman has a sudden severe headache, stiff neck and photophobia. CSF is xanthochromic, and CT angiography shows an anterior communicating artery aneurysm.
Which structures are most at risk from its rupture?
A 30-year-old woman with optic neuritis has periventricular MRI lesions and CSF oligoclonal bands. She improves on steroids but relapses 6 months later.
Which medication most effectively prevents relapses?
A 45-year-old man has progressive memory loss and behavior change. MRI shows atrophy of both anterior temporal lobes, his mother had similar symptoms, and genetic testing shows a progranulin mutation.
Which pathologic protein accumulates?
A couple has a child with spinal muscular atrophy type 1. Both parents are carriers. They want prenatal diagnosis next time.
Which test is most appropriate?
A 30-year-old woman exposed to a toxin that blocks fast sodium channel inactivation has paralysis and prolonged contractions.
What is the most likely effect on the action potential?
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